Antimicrobial Use and Stewardship

CDFA-AUS • 1220 N Street, Sacramento, CA 95814 • 916-576-0300

About the AUS Program

California Senate Bill 27 (Hill), signed by Governor Brown on October 10, 2015, resulted in additions to the California Food and Agricultural Code (Division 7, Chapter 4.5, Sections 14400-14408) that address the use of medically important antimicrobial drugs in livestock, development of antimicrobial stewardship guidelines and best management practices, and surveillance of antimicrobial use as well as antimicrobial resistance patterns in bacteria.

In California, effective January 1st of 2018, over the counter injectable and all other medically important antimicrobials must be administered with a prescription or veterinary feed directive (VFD) ordered by a California licensed veterinarian under a valid veterinarian-client-patient relationship (VCPR). The law also requires the California Department of Food & Agriculture to ensure that livestock producers in rural areas continue to have timely access to antimicrobials.

Note that these changes are separate from the federal regulations regarding antimicrobials in feed and water that became effective on January 1, 2017.


Livestock: Use of Antimicrobial Drugs (FAC § 14400 – 14408) California law effective as of January 1st, 2018 Livestock Drugs (FAC § 14200 – 14390) Existing California law referenced in the Livestock: Use of Antimicrobial Drugs law.
2018 Strategic Plan Finalized and approved plan to continue implementation through the AUS program in 2018. 2017 Strategic Plan CDFA AUS finalized and approved plan to implement the aforementioned law. April 2018 Quarterly Update Overview of accomplishments made since the November 2017 Ad Hoc Advisory Meeting. November 2017 Quarterly Update Overview of accomplishments made since June 2017 Ad Hoc Advisory Meeting. June 2017 Quarterly Update Overview of accomplishments made since previous Quarterly Advisory Meeting.
GFI #152 Appendix A identifies Medically, Highly, and Critically important antimicrobials. If an antimicrobial you use fits within a named class then FDA will consider it important. FDA also considers sulfonamides as important. GFI #209 Introduces veterinary oversight and only necessary use as guiding principles. GFI #213 Explains the changes FDA wants to see for the mass use of antimicrobial drugs (Feed and Water).

CDFA Animal Health &
Food Safety Services