Antimicrobial Use and Stewardship

CDFA-AUS • 1220 N Street, Sacramento, CA 95814 • 916-576-0300

About the AUS Program

California Senate Bill 27 (Hill), signed by Governor Brown on October 10, 2015, resulted in additions to the California Food and Agricultural Code (Division 7, Chapter 4.5, Sections 14400-14408) that address the use of medically important antimicrobial drugs in livestock, development of antimicrobial stewardship guidelines and best management practices, and surveillance of antimicrobial use as well as antimicrobial resistance patterns in bacteria.

In California, effective January 1st of 2018, over the counter injectable and all other medically important antimicrobials must be administered with a prescription or veterinary feed directive (VFD) ordered by a California licensed veterinarian under a valid veterinarian-client-patient relationship (VCPR). The law also requires the California Department of Food & Agriculture to ensure that livestock producers in rural areas continue to have timely access to antimicrobials.

Note that these changes are separate from the federal regulations regarding antimicrobials in feed and water that became effective on January 1, 2017.


Livestock: Use of Antimicrobial Drugs (FAC § 14400 – 14408) California law effective as of January 1st, 2018 Livestock Drugs (FAC § 14200 – 14390) Existing California law referenced in the Livestock: Use of Antimicrobial Drugs law. Proposed Regulations The comment period is CLOSED. For more information please email
2017 Strategic Plan CDFA AUS finalized and approved plan to implement the aforementioned law. June 2017 Quarterly Update Overview of accomplishments made since previous Quarterly Advisory Meeting.

The Antimicrobial Use and Stewardship (AUS) program requires the coordination of the Animal Health and Food Safety Services (AHFSS) division and the Inspection Services Division (ISD).

Animal Health and Food Safety Services
Inspection Services Division Antimicrobial Use and Stewardship

These are two different divisions within the California Department of Food and Agriculture, building upon their existing framework to contribute expertise, staff and structure to the AUS program.

Although they are inherently linked through the program mandate, each division’s staff provides support in different way, as you can see below.

Division of Responsibilities

  • Outreach/Education to Vets, Producers, and members of the public
  • Stewardship
  • Voluntary surveys of usage practices
  • Veterinarian access for producers and clarification of “Veterinarian-Client-Patient Relationship
  • Producer resources for judicious use of MIADs
  • Training for outreach to veterinarians, producers and public
  • Restricted Livestock Drug (RLD) Retailer Licenses (including MIAD sales)
  • RLD Sales Logs (including new MIAD requirements)
  • Enforcement of RLD Licenses, RLD Sale Log collection, and Feed Manufacturers
  • Feed Manufacturers Compliance for VFDs
  • Training for outreach to RLD Retailers and Feed Manufacturers
CDFA Animal Health and Food Safety Services CDFA Inspection Services
GFI #152 Appendix A identifies Medically, Highly, and Critically important antimicrobials. If an antimicrobial you use fits within a named class then FDA will consider it important. FDA also considers sulfonamides as important. GFI #209 Introduces veterinary oversight and only necessary use as guiding principles. GFI #213 Explains the changes FDA wants to see for the mass use of antimicrobial drugs (Feed and Water).

CDFA Animal Health &
Food Safety Services