Antimicrobial Use and Stewardship

CDFA-AUS  •  1220 N Street, Sacramento, CA 95814  •  916-576-0300

Resources & Outreach

The AUS program provides resources for all stakeholders, including veterinarians and producers, about the effort in California to reduce antimicrobial resistance in livestock. Below please find outreach and educational materials, best management practices and guidance documents, programmatic reports, and other publications produced or supported by the AUS program. Information on AUS presentations and events, past and upcoming, is also provided. Additionally, other resources related to antimicrobial resistance education and research are listed.

Frequently Asked Questions: Answers to frequently asked questions regarding the AUS program.
English  |  Spanish (Español: Preguntas Frequentes)
Requirements for Prescription Antibiotics: Existing requirements for veterinary prescriptions, options for filling prescriptions, and establishing a valid veterinarian-client-patient relationship (VCPR).
Veterinarian   | Producer | Spanish (Español: Requisitos para Antibióticos Recetados)
AUS Annual Reports: Description and highlights of program activities reported for each fiscal year. Attached appendices provide more detailed information for a selection of AUS' studies and projects.
AUS 2020 Annual Report
AUS 2019 Annual Report | News Release
Veterinary Feed Directive (VFD) Summary Reports: Annual summaries of manufacturing and distribution data for California medicated feed containing a VFD drug or combination VFD drugs, by VFD order written by a licensed veterinarian.
2019 Veterinary Feed Directive Summary Report
Summary Report Veterinary Feed Directive 2017 – 2019 Q1
AUS Report to the Legislature: The AUS Report to the Legislature, published in 2019, fulfills the mandate in FAC 14405 (d) by providing the results of the program’s outreach activities and monitoring efforts during its first years of implementation.
AUS Report to the Legislature | News Release
AUS Strategic Plans: AUS publishes its Strategic Plans as appropriate to update stakeholders on programmatic goals and plans for implementation.
2018 Strategic Plan
CDFA AUS – Best Management Practices (BMPs) // Vaccine Handling Guidelines: Five infographics providing foundational knowledge of proper vaccine handling to ensure an effective vaccination program.

CDFA AUS – Best Management Practices (BMPs) // Vaccine Handling Guidelines – Resources for Veterinarians: These veterinary considerations offer a more in-depth instruction on the nuances of creating an effective vaccination program, along with additional scientific resources.

CDFA AUS – BMPs for Vaccine Handling Guidelines | Español: CDFA AUS - Buenas prácticas de manejo // Pautas de Manejo de Vacunas
CDFA AUS – BMPs for Vaccine Handling Guidelines - Resources for Veterinarians
Antimicrobial Stewardship Principles: Please visit the AUS Antimicrobial Stewardship page. Guidelines for Judicious Use of Antimicrobials: These guidelines are intended to support decision-making surrounding responsible antibiotic use, under the guidance of a veterinarian in compliance with state and federal laws.
Guidelines for Judicious Use of Antimicrobials in Livestock
Guidelines for Veterinarians: Judicious Use of Antimicrobials in Livestock
Responsible Antibiotic Use infographic
Antimicrobial Stewardship Planning Checklist: Resources to promote or support veterinarians engaging in conversations with their livestock producers regarding broad, non–species specific health related topics.
Antimicrobial Stewardship Planning Checklist One–Page | Español: Lista de verificación para la planificación de administración de antimicrobianos de una página
Antimicrobial Stewardship Planning Checklist Workbook | Español: Cuaderno de trabajo de la lista de verificación para la planificación de administración de antimicrobianos
Veterinarian–Client–Patient Relationship (VCPR) Resources: Establishing a veterinarian–client–patient relationship (VCPR) is an essential first step in the development of an Antimicrobial Stewardship Plan.
VCPR Practice Model – Youth Agriculture
VCPR Example – Agent Authorization
2017 Cow Calf Survey: Summary findings from AUS’ 2017 survey of antibiotic use and stewardship on California’s cow calf operations.
2017 Cow Calf Survey | Español: Encuesta de Terneros 2017
2018 Commercial Sheep Survey: Summary findings from AUS’ 2018 survey of antibiotic use and stewardship on California’s commercial sheep operations.
2018 Commercial Sheep Survey | Español: Encuesta de Ovejas Comerciales 2018
Partnering for Dairy Antimicrobial Stewardship: A Conference for Farmers and Veterinarians in the West (July 2020)
Recordings: July 8 | July 15 | July 22 | July 29
Upcoming: Visit here for information on upcoming AUS presentations, events, and opportunities to get involved with the program.
Distinguishing Between US and CA Antibiotic Laws: Easy-to-read flowchart explains medically important antimicrobial drugs (MIADs) and related laws.
English | Spanish (Español: ¿Cómo Distinguir entre las leyes sobre antibióticos de EE.UU. y California (CA)? Gráfico)
Veterinary Feed Directive (VFD) Resources: Resources related to VFDs and VFD orders. For more information on VFDs, please visit the CDFA FFLDRS Livestock Drug Program page.
CDFA Feed Program's VFD page
VFD Checklist
Common Issues on Veterinary Feed Directives
Filling a Veterinary Feed Order
Confidentiality in Data Reporting: Brochure with information on AUS’ approach to confidentiality in data reporting. AUS Surveys & Studies Resources: Materials addressing the who, what, why, and how the AUS program is collecting information on California animal agriculture and what you can do to help. For more information on AUS Surveys & Studies, please visit the Surveys & Studies page.
AUS Surveys & Studies Trifold
AUS Surveys & Studies Participation Flier
Antimicrobial Stewardship During COVID-19 Pandemic: COVID-19 has brought numerous challenges to the animal production industry. This infographic lists considerations for the continuation of antimicrobial stewardship in livestock during the COVID-19 pandemic.
In addition to materials, events, and research produced by the AUS team, the AUS program provides funding and support for a number of studies, projects, publications, and other resources led by external partners. Below find information on work produced with AUS funding and/or collaborative support. Minimum Inhibitory Concentration (MIC) Resources: MIC testing is one method of measuring the susceptibility of bacteria to antimicrobial drugs. It is essential for AUS to know how to best use and interpret this type of data.

Alec Michael, Todd Kelman, Maurice Pitesky. Overview of Quantitative Methodologies to Understand Antimicrobial Resistance via Minimum Inhibitory Concentration. Animals 2020, 10(8), 1405;
Opportunities to Reduce Dry Cow Therapy: An article was recently published in the publication Progressive Dairy, promoting an AUS funded study that explores the use of Selective Dry Cow Therapy in dairy herds and the opportunity to reduce the use of antibiotics in dairy production systems, which may also be an economic opportunity for dairy farmers.

Hollister, Julia. “Dry Cow Therapy: A Prescription for Success.” Progressive Dairy, 26 Aug. 2020,
Antimicrobial Susceptibility and Genomic Testing: Antibiotic resistance, particularly to certain classes of drugs, is recognized as a growing threat and is caused by previously described families of genes. While many studies evaluate the presence of these genes, few or no studies have looked at three critical groups of genes together in one test panel. Through antimicrobial susceptibility and genomic testing using a novel test panel, this research evaluates specific antimicrobial resistance patterns in Salmonella isolates from California dairy cattle over a period of 14 years. This novel test panel could potentially increase access to rapid screening for resistance in the clinical setting.

Basbas C, Byrne BA, Chigerwe M, Escobar ED, Hodzic E, Pires AFA and Pereira RV (2021) Detection of Cephalosporin and Fluoroquinolone Resistance Genes via Novel Multiplex qPCR in Fecal Salmonella Isolates From Northern Californian Dairy Cattle, 2002–2016. Front. Microbiol. 12:601924. doi: